1.2008/06-至今，浙江大学生命科学学院，教授
2.2003/06-2008/05，国家海洋局第三海洋研究所，研究员
3.2000/08-2003/05，新加坡国立大学生物学，博士后，合作导师：邱才良教授
4.1992/07-1997/01，安徽农业大学农学系，讲师

1. 国家自然科学基金重点项目，30830084，非编码小RNA 在对虾免疫中作用的分子机制，2009/01-2012/12，175万元，已结题，主持
2. 国家高技术研究发展计划（863计划），2010AA09Z443，对虾吞噬、凋亡免疫反应的关键基因及其抗病毒作用，2010/01-2012/12，138万元，已结题，主持
3. 中国大洋协会，DY125-15-E-01，深海热液口嗜热细菌与噬菌体之间的相互作用研究,2012/01-2015/09，270万元，已结题，主持
4. 国家自然科学基金面上项目，41276152，深海热液区嗜热菌噬菌体裂解宿主的机制，2013/01-2016/12，86万元，已结题，主持
5. 国家自然科学基金重点项目，31430089，miRNA在对虾-病毒互作中的作用机理，2015/01-2019/12，332万元，主持
6. 中国大洋协会，DY135-B-04，深海病毒多样性与病毒安全性评估，2017/01-2020/12，1200万元，主持

1. 近5年内发表的5篇代表性论著
[1] G Yang, Y Gong, Q Wang, L Wang, X Zhang*. 2017. miR-100 antagonism triggers apoptosis by inhibiting ubiquitination-mediated p53 degradation. Oncogene 36 (8): 1023-1037
[2] Yulei Chen, Siyuan Zhang, Qizhi Wang, Xiaobo Zhang*. 2017. Tumor-recruited M2 macrophages promote gastric and breast cancer metastasis via M2 macrophage-secreted CHI3L1 protein. Journal of Hematology & Oncology 10: 36
[3] Tianliang He, Hongyun Li, Xiaobo Zhang*. 2017. Deep-sea hydrothermal vent viruses compensate for microbial metabolism in virus-host interactions. mBio 8 (4): e00893-17
[4] Fan Yang, Jun Wei, Song Zhang, Xiaobo Zhang*. 2017. Shrimp miR-S8 suppresses the stemness of human melanoma stem-like cells by targeting the transcription factor YB-1. Cancer Research 77 (20): 5543-5553
[5] Tianliang He, Min Jin, Chenxi Xu, Zhongjun Ma, Fufang Wu, Xiaobo Zhang*. 2018. The homeostasis-maintaining metabolites from bacterial stress response to bacteriophage infection suppress tumor metastasis. Oncogene 37: 5766-5779
2. 近5年内发表的其余论著
[1] Tianzhi Huang, Yalei Cui, Xiaobo Zhang*. 2014. Involvement of viral microRNA in the regulation of antiviral apoptosis in shrimp. Journal of Virology 88(5):2544-2554
[2] Min Jin, Yanjiang Chen, Chenxi Xu, Xiaobo Zhang*. 2014. The effect of inhibition of host MreB on the infection of thermophilic phage GVE2 in high temperature environment. Scientific Reports 4 (4823): 1-8
[3] Geng Yang, Yi Gong, Qizhi Wang, Yumeng Wang, Xiaobo Zhang*. 2015. The role of miR-100-mediated Notch pathway in apoptosis of gastric tumor cells. Cellular Signalling 27: 1087-1101
[4] Yulei Chen, Chunxia Jiang, Min Jin, Yi Gong, Xiaobo Zhang*. 2015. The role of Rab6 GTPase in the maturation of phagosome against Staphylococcus aureus. The International Journal of Biochemistry & Cell Biology 61: 35-44
[5] Yi Gong, Tianliang He, Lu Yang, Geng Yang, Yulei Chen, Xiaobo Zhang*. 2015. The role of miR-100 in regulating apoptosis of breast cancer cells. Scientific Reports 5: 11650; doi: 10.1038/srep11650