人才队伍
秦启伟
秦启伟
职称:教授
单位:华南农业大学
邮箱:qinqw@scau.edu.cn
创新团队:海洋生命过程与生物资源利用
职位:核心成员
教育经历
1. 1982/09-1986/06,北京师范大学,生物学系,学士
2. 1988/09-1991/06,武汉大学生物学系,硕士
3. 1991/09-1994/07,中国科学院,水生生物研究所,博士
科研与学术工作经历
1. 1994/07-1997/02, 中国科学院, 南海海洋研究所, 助理研究员、副研究员
2. 1997/02-1998/04, 日本国立水产养殖研究所, 博士后
3. 1998/04-2004/08, 新加坡国立大学, 热带海洋研究所, 研究员
4. 2004/01-2009/02, 中山大学, 生命科学学院,教授、博导
5. 2009/03-2016/04, 中国科学院南海海洋研究所, 研究员、研究室主任、所长助理
6. 2016/04-至今, 华南农业大学, 海洋学院, 教授、博导、院长
科研项目
1. 国家重点基础研究发展计划课题, 2018YFC0311302,海水养殖鱼类病毒疫苗产品开发及应用实践,2018/8 – 2021/12,509万元,在研,主持
2. 国家自然科学基金重点项目,31930115,石斑鱼虹彩病毒SGIV调控宿主细胞代谢的作用机制,2020/01 – 2020/12,303万元,在研,主持
3. 广东省海洋经济发展专项,GDME-2018C002,重要海洋病原生物新型核酸检测产品的开发应用,2018/05 – 2020/05,500万元,结题,主持
4. 国家自然科学基金重点项目,31330082,在单病毒粒子水平研究石斑鱼虹彩病毒SGIV侵染宿主细胞的机制,2014/01 – 2018/12,324万元,结题,主持
5. 国家基础青年科学基金,30725027,水产保护学,2008/01 – 2011/12,200万元,结题,主持
研究成果
① 近5年内发表的5篇代表性论著:
1.Zhang X, Liu Z, Li C, Zhang Y, Wang L, Wei J*, Qin Q*. Grouper TRADD Mediates Innate Antiviral Immune Responses and Apoptosis Induced by Singapore Grouper Iridovirus (SGIV) Infection. Front Cell Infect Microbiol. 2019 Sep 18;9:329.
2. Li C, Liu J, Zhang X, Wei S, Huang X, Huang Y, Wei J*, Qin Q*. Fish Autophagy Protein 5 Exerts Negative Regulation on Antiviral Immune Response Against Iridovirus and Nodavirus. Front Immunol. 2019 Mar 19;10:517.
3. Zhang Y, Wang LQ, Huang XH, Wang SW, Huang Y*, Qin Q*. Fish Cholesterol 25-Hydroxylase Inhibits Virus Replication via Regulating Interferon Immune Response or Affecting Virus Entry. Frontiers in Immunology, 2019, 10 ( 322): 1-14.
4. Wei J#, Huang Y#, Zhu W, Li C, Huang X, Qin Q*. Isolation and identification of Singapore grouper iridovirus Hainan strain (SGIV-HN) in China. Archives of Virology, 2019, 164(7): 1869-1872.
5. Zhou L, Li P, Yang M, Yu Y, Huang Y, Wei J, Wei S*, Qin Q*. Generation and characterization of novel DNA aptamers against coat protein of grouper necrosis virus with antiviral activities and delivey potential in grouper cells. Antiviral Research, 2016,129: 104-114.
② 近5年内发表的其余论著:
1. Front Immunol. 2019 Mar 19;10:517. doi: 10.3389/fimmu. 2019. 00517.
2. Wei S, Yu Y, Qin Q. Establishment of a new fish cell line from the caudal fin of golden pompano Trachinotus ovatus and its susceptibility to iridovirus. J Fish Biol. 2018 Jun;92(6):1675-1686.
3. Yu Y, Huang X, Liu J, Zhang J, Hu Y, Yang Y, Huang Y*, Qin Q*. Fish TRIM32 functions as a critical antiviral molecule against iridovirus and nodavirus. Fish Shellfish Immunol. 2017, 60:33-43.
4. Yu Y, Huang Y, Wei S, Li P, Zhou L, Ni S, Huang X*, Qin Q*. A tumour necrosis factor receptor-like protein encoded by Singapore grouper iridovirus modulates cell proliferation,apoptosis and viral replication. Journal of General Virology. 2016, 97(3):756-66
5. Guo M, Wei J, Huang X, Zhou Y, Yan Y, Qin Q. JNK1 derived from orange-spotted grouper, Epinephelus coioides, involving in the evasion and infection of Singapore grouper iridovirus (SGIV). Frontiers in Microbiology. 2016, 7:121.
6. Wang W, Huang Y, Yu Y, Yang Y, Xu M, Chen X, Ni S, Qin Q*, Huang X*. Fish TRIM39 regulates cell cycle progression and exerts its antiviral function against iridovirus and nodavirus. Fish & Shellfish Immunology. 2016,50:1-10.
7. Huang Y, Yu Y, Yang Y, Yang M, Zhou L, Huang X*, Qin Q*. Antiviral function of grouper MDA5 against iridovirus and nodavirus. Fish & Shellfish Immunology. 2016,54:188-96.
8. Huang Y, Yu Y, Yang Y, Yang M, Zhou L, Huang X*, Qin Q*. Fish TRIM8 exerts antiviral roles through regulation of the proinflammatory factors and interferon signaling. Fish & Shellfish Immunology. 2016,54:435-444.
9. Li P, Wei S, Zhou L, Yang M, Yu Y, Wei J, Jiang G*, Qin Q*. Selection and characterization of the novel DNA-aptamers specifically recognized Singapore grouper iridovirus (SGIV) infected fish cells. J Gen Virol. 2015, doi: 10.1099/jgv.0.000270
10. Huang X, Huang Y, Xu L, Wei S, Ouyang Z, Feng J, Qin Q. Identification and characterization of a novel lymphocystis disease virus isolate from cultured grouper in China. J Fish Dis. 2015, 38: 379-387.
11. Pan Y#, Wang S#, Shan Y, Zhang D, Gao J, Zhang M, Liu S, Cai M, Xu H, Li G, Qin Q*, Wang H*. Ultrafast tracking of a single live virion during the invagination of a cell membrane. Small. 2015, 11: 2782-2788.
12. Li P, Zhou L, Yu Y, Yang M, Ni S, Wei S, Qin Q. Characterization of DNA aptamers generated against the soft-shelled turtle iridovirus with antiviral effects. BMC Vet Res. 2015, 11: 245.