人才队伍
彭博
彭博
职称:教授
单位:中山大学
邮箱:pengb26@mail.sysu.edu.cn
创新团队:海洋生命过程与生物资源利用
职位:核心成员
教育经历
1. 2000/09 – 2004/06,厦门大学,生命科学学院,学士
2. 2005/08 – 2008/05,新加坡国立大学,生物系,硕士,导师:Leung, Ka-yin
3. 2008/08 – 2012/12,The University of Texas at El Paso,Department of Biological Sciences,博士,导师:Zhang, Jianying
科研与学术工作经历
1. 2016/02-至今,中山大学,生命科学学院,教授
2. 2013/04-2015/07,Lawrence Berkeley National Lab,Molecular Foundry,博士后,合作导师:Ren, Gang
科研项目
1. 国家自然科学基金优秀青年科学基金项目,31822058,低抗和无抗控制水产耐药菌的应用基础研究,2019/01-2021/12,130万元,在研,主持
2. 国家自然科学基金面上项目,31842602, 丙酮酸循环介导抗生素入胞机制的研究, 2019/01 – 2022.12,在研,主持
3. 科技部重点研发计划“蓝色粮仓”,水产动物疫病发生的分子基础与免疫机制,2018YFD0900501, 2019/01- 2022.12, 80万元,在研,参与
4. 青岛海洋科学与技术国家实验室开放基金、代谢逆转病原菌血清抗性的研究, 2019.01-2020.12, 在研,主持
5. 国家自然科学基金面上项目,31672656,ATP提高耐药菌对抗生素敏感性的研究, 2017.01-2020.12,在研,主持
6. 科技部国家重点研发计划,2016YFD0501307,病原菌耐药性消减技术,2016.07-2020.12, 在研,主持
研究成果
1. 近5年内发表的5篇代表性论著
[1] Jiang M, Gong QY, Lai SS, Cheng ZX, Chen ZG, Zheng J, Peng B*. Phenylalanine enhances innate immune response to clear ceftazidime-resistant Vibrio alginolyticus in Danio rerio, Fish Shellfish Immunology (1050-4648), 2019,84:912-919
[2] Su YB#, Peng B#*, Li H#, Cheng ZX, Zhang TT, Zhu JX, Li D, Li MY, Ye JZ, Du CC, Zhang S, Zhao XL, Yang MJ, Peng XX*. Pyruvate cycle increases aminoglycoside efficacy and provides respiratory energy in bacteria. Proc. Natl. Acad. Sci USA, 2018, 115 (7) E1578-E1587
[3] Cheng ZX, Gong QY, Wang Z, Chen ZG, Ye JZ, Li J, Wang J, Yang MJ, Ling XP, Peng B*. Edwardsiella tarda tunes tricarboxylic acid cycle to evade complement-mediated killing, Frontiers in Immunology, 2017, 8:1706
[4] Zeng ZH, Du CC, Liu SR, Li H, Peng XX, Peng B*. Glucose enhances tilapia against Edwardsiella tarda infection through metabolome reprogramming. Fish & Shellfish Immunology 2017, 61, 34-43
[5] Peng B#, Su YB#, Li H#, Han Y, Guo C, Tian YM, Peng XX*. Exogenous alanine or/and glucose plus kanamycin kills antibiotic-resistant bacteria. Cell Metabolism 2015, 21(2): 249-261
2. 近5年内发表的其余论著
[1] Ji X, Zou J, Peng HB, Stolle AS, Xie RQ, Zhang HJ, Peng B, Mekalanos JJ, Zheng J. Alarmone Ap4A is elevated by aminoglycoside antibiotics and enhances their bactericidal activity. Proc. Natl. Acad. Sci USA, 2019, 116(19): 9578-9585
[2] Ye JZ, Su YB, Lin XM, Lai SS, Li WX, Ali F, Zheng J, Peng B*. Alanine enhances aminoglycosides-induced ROS production as revealed by proteomic analysis. Frontiers in Microbiology, 2018,9:29
[3] Ye JZ, Lin XM, Cheng ZX, Su YB, Li WX, Ali FM, Zheng J, Peng B*. Identification and efficacy of glycine, serine and threonine metabolism in potentiating kanamycin-mediated killing of Edwardsiella piscicida. J. Proteomics, 2018, 183:34-44
[4] Peng B#, Lin XP, Wang SN, Yang MJ, Peng XX, Li H. Polyvalent protective immunogens identified from outer membrane proteins of Vibrio parahaemolyticus and their induced innate immune response. Fish shellfish Immunol 2018, 72:104-110
[5] Xie RQ, Zhang XH, Zhao Q, Peng B, Zheng J. Analysis of global prevalence of antibiotic resistance in Acinetobacter baumannii infections disclosed a faster increase in OECD countries. Emerg. Microbe. Infect. 2018, 7:31